FIELD: pharmaceuticals.
SUBSTANCE: invention refers to a pharmaceutical product in the form of a container containing a liquid preparation. Liquid preparation contains: (A) dibutylhydroxytoluene, (B) pranoprofen and / or a pharmaceutically acceptable salt thereof and (C) at least one compound selected from the group consisting of cromoglicic acid, allantoin, glycyrrhizic acid, chlorpheniramine, and pharmaceutically acceptable salts thereof. Container comprises container body for liquid preparation, nozzle with outlet hole, through which liquid preparation contained in container body can be poured, and cap for outlet opening closing. At least one surface selected from the surface of the walls of the inner space of the spout and the wall surface on the outlet side of the cap contains a resin, which contains polybutylene terephthalate. Also disclosed is a method of stabilizing dibutylhydroxytoluene in a liquid preparation.
EFFECT: invention increases heat stability of dibutylhydroxytoluene and suppresses reduction of its content over time in a liquid preparation, which contains dibutylhydroxytoluene and pranoprofen and / or salt thereof.
12 cl, 6 dwg, 4 tbl, 2 ex
