ACHS/VNIIZZH/CV-1 STRAIN OF AFRICAN SWINE FEVER, WITH DECREASED VIRULENCE FOR PIGS, FOR VIROLOGIC, DIAGNOSTIC, MOLECULAR-GENETIC AND SURVEILLANCE STUDIES Russian patent published in 2018 - IPC C12N7/00 

Abstract RU 2675535 C1

FIELD: veterinary science.

SUBSTANCE: invention relates to the field of veterinary virology and concerns a new strain of African swine fever virus of 2 genotype VIII serotype Asfarviridae family, Asfivirus genus, deposited in the collection of FGBI “Federal Centre for Animal Health” (FGBI “ARRIAH”) under the registration number of the strain of African swine fever virus AChS/VNIIZZh/CV-1 (D). Characterized strain is obtained by adaptation by successive passaging in a transplanted culture of kidney cells of an African green monkey (CV-1). Presented strain has a moderate infectious activity, accumulates in the culture of bone marrow cells and CV-1 in the titer of 6.0–7.0 lg GAdE 50/cm3. Virulence for pigs of all age groups when administered intramuscularly does not exceed 37.5 %.

EFFECT: presented virus strain can be used to obtain antigen-containing drugs and serotype-specific serum for diagnostic studies.

4 cl, 3 tbl, 1 dwg, 4 ex

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Authors

Vlasova Natalya Nikiforovna

Zhukov Ivan Yurevich

Mazlum Ali

Sharypova Darya Viktorovna

Pershin Andrej Sergeevich

Igolkin Aleksej Sergeevich

Dates

2018-12-19Published

2018-05-15Filed