FIELD: veterinary.
SUBSTANCE: invention relates to the field of veterinary virology and genetic engineering and concerns a recombinant strain of the African swine fever virus. ΔCongoCD2v strain of the African swine fever (ASF) virus with the deletion of the gene EP402R (CD2v) containing the EGFP reporter gene under the control of the p72 promoter is suggested. Claimed strain was obtained from the KK-262 strain of the ASF virus by homologous recombination and deposited in the collection of microorganism cultures of the Federal Research Centre of Virology and Microbiology under №3148.
EFFECT: strain can be used to study the role of the CD2v protein of the ASF virus in the virus reproduction in cell cultures, in susceptible animals, as well as its functions in modulating the immune response.
1 cl, 1 dwg, 1 tbl, 3 ex
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Authors
Dates
2018-05-21—Published
2016-04-20—Filed