STABLE ANTI-TUMOR MEDICINE, METHOD FOR ITS PREPARATION AND APPLICATION Russian patent published in 2018 - IPC A61K31/4166 A61K31/30 A61K47/30 A61K9/08 C07F1/08 

Abstract RU 2676279 C1

FIELD: pharmaceuticals.

SUBSTANCE: group of inventions relates to the chemical and pharmaceutical industry and is an anticancer drug for the treatment of breast cancer, which is a solution for injecting, including as active substance complex (5Z,5'Z)-2,2'-(ethane-1,2-diyldisulfanyldiyl)bis(5-(2-pyridylmethylene)-3-allyl-3,5-dihydro-4H-imidazol-4-one) with copper (II) chloride, a solvent including dimethyl sulphoxide, polysorbate 20 and poloxamer 407, and the Hemodez H diluent. Also, the inventions are represented by a method for preparing this drug, including adding the active substance in powder form to a previously prepared solvent, then sonicating the solution until the active ingredient is completely dissolved and diluting the resulting solution with Hemodez H to a therapeutically effective concentration of the active ingredient in the drug. Invention includes a method for treating breast cancer, which includes the injection administration of said drug, prepared by this method before 60 minutes after preparation of the drug in a therapeutically effective amount.

EFFECT: group of inventions ensures the stability of the obtained product within 60 minutes from the moment of its preparation until the introduction into the patient.

5 cl, 2 tbl, 325 ex

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RU 2 676 279 C1

Authors

Sakharov Dmitrij Andreevich

Dates

2018-12-27Published

2017-11-01Filed