FIELD: chemistry.
SUBSTANCE: invention relates to a compound which is tert-butyl-N-[2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]-3,5-difluorophenyl}ethyl]-L-alaninate or a pharmaceutically acceptable salt thereof and has the ability to inhibit the activity of the p38 MAP-kinase (mitogen-activated protein kinase) enzyme.
EFFECT: invention also relates to a pharmaceutical composition comprising said compound and a method of inhibiting the p38 MAP kinase enzyme.
7 cl, 2 tbl, 1 ex
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| QUINAZOLINE DERIVATIVES | 2004 |
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| KINASE INACTIVATORS AND METHODS OF THEIR APPLICATION | 2007 |
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| (+)-5-(3,4-DIFLUOROPHENYL)-5-[(3-METHYL-2-OXOPYRIDIN-1(2H)-YL)METHYL]IMIDAZOLIDINE-2,4-DIONE AND DRUG CONTAINING SAME | 2014 |
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RU2486178C2 |
| 3-(5)-HETEROARYL-SUBSTITUTED PYRAZOLES AS KINASE P38 INHIBITORS | 1998 |
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| 6-ALCOXYPYRIDOPYRIMIDINES AND PHARMACEUTICAL COMPOUND POSSESSING ACTIVITY OF MAP p38 KINASE INHIBITORS | 2003 |
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