(+)-5-(3,4-DIFLUOROPHENYL)-5-[(3-METHYL-2-OXOPYRIDIN-1(2H)-YL)METHYL]IMIDAZOLIDINE-2,4-DIONE AND DRUG CONTAINING SAME Russian patent published in 2018 - IPC C07D401/06 A61K31/4439 A61P17/00 A61P37/08

Abstract RU 2668072 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to (+)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridin-1(2H)-yl)methyl]imidazolidine-2,4-dione or salt thereof. Also provided is a drug having a tumor necrosis factor-alpha (TNF-alpha) converting enzyme (TACE) inhibitory effect, containing as the active ingredient (+)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridin-1(2H)-yl)methyl]imidazolidine-2,4-dione or a salt thereof.

EFFECT: obtained is a novel compound and a pharmaceutical agent based on it that can be used in medicine for the treatment of psoriasis.

20 cl, 3 tbl, 1 ex

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RU 2 668 072 C2

Authors

Kamei Noriyuki

Kamimura Daigo

Sumikava Jositake

Tokuoka Sota

Dates

2018-09-27—Published

2014-06-06—Filed