SYNTHETIC LETHALITY AND TREATMENT OF CANCER Russian patent published in 2019 - IPC A61K31/4439 A61P35/00 

Abstract RU 2676697 C2

FIELD: medicine.

SUBSTANCE: present group of inventions relates to medicine, namely to oncology, and concerns the treatment of cancer. For this purpose, cancer patients who are deficient in the isomer of the enzyme N-myristoyltransferase 2 (NMT2) are identified. Treatment of this group of patients is carried out by administering an NMT inhibitor or NMT1 isoenzyme.

EFFECT: this provides an increase in the effectiveness of treatment of this group of patients, since cancer deficient in NMT2 is most sensitive to treatment with NMT inhibitors.

16 cl, 8 tbl, 38 ex, 42 dwg

Similar patents RU2676697C2

Title Year Author Number
SYNTHETIC LETHALITY AND THE TREATMENT OF CANCER 2012
  • Bertom Lyuk G.
  • Boshamp Ervan
  • Perinpanayagam Konganig Maneka Ann
  • Yap Chuiee
RU2665952C2
COMBINED IMMUNOTHERAPEUTIC APPROACH TO CANCER TREATMENT 2015
  • Szalej Aladar
  • Minev Boris
RU2716821C2
PHARMACEUTICAL COMBINATIONS FOR TREATING A MALIGNANT TUMOR 2017
  • Klinghoffer, Richard
  • Dey, Joyoti
RU2726367C2
MITOSIS INHIBITORS FOR INTENSIFICATION OF APOPTOSIS PROCESS IN THERAPY 2009
  • Tankvist Brajan Dzh.
  • Voker Dunkan Kh.
  • Vosner Richard Donal'D
RU2519145C2
ANTIBODIES AGAINST CCR7 RECEPTOR FOR CANCER TREATMENT 2006
  • Mun'Os Kall'Ekha Sesilija
  • Al'Fonso Peres Manuehl' Khesus
  • Lopes Khiral' Sonia
RU2404808C2
SYNERGISTIC COMBINATIONS OF AURISTANE 2015
  • Sapra, Puja
  • Shor, Boris
RU2717570C2
SMALL MOLECULES FOR TREATMENT OF CANCER, INHIBITION OF CHEMOKINE ACTIVITY AND/OR INDUCTION OF CELL DEATH 2020
  • Peled, Amnon
  • Abraham Karni, Michal
  • Eizenberg, Orly
RU2814917C2
TREATMENT OF B-CELLULAR MALIGNANT TUMORS USING ANTI-CD40L ANTIBODIES IN COMBINATION WITH ANTI-CD20 ANTIBODIES AND/OR BY CHEMOTHERAPY AND RADIOTHERAPY 2000
  • Khanna Nabil
  • Kharikharan Kandasami
RU2305561C2
COMBINATION OF CHEKPOINT-KINASE 1 INHIBITORS AND WEE 1 KINASE INHIBITORS 2011
  • Dejvis Kertis D.
  • Gros Stefan
RU2627841C2
TREATMENT OF CANCER, USING ANTIBODY TO SEMAPHORIN 4D IN COMBINATION WITH EPIGENETIC MODULATING AGENT 2018
  • Evans, Elizabet
  • Smit, Ernest S.
  • Zauderer, Moris
RU2783535C2

RU 2 676 697 C2

Authors

Bertom Lyuk G.

Perinpanayagam Konganig Maneka Ann

Yap Chuiee

Boshamp Ervan

Dates

2019-01-10Published

2013-10-30Filed