HAEE PEPTIDE COPPER COMPLEX FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES Russian patent published in 2022 - IPC C07K5/117 A61K38/07 A61P25/28 

Abstract RU 2784732 C1

FIELD: copper complexes.

SUBSTANCE: invention relates to a copper complex of the formula [Cu(HAEE)]mXn, where Cu is a doubly charged copper (II) cation, m=1 for singly and doubly charged anions, m=3 for triply charged anions, HAEE is a synthetic peptide acetylated at N -terminus and amidated at the C-terminus, with the amino acid sequence His-Ala-Glu-Glu, X is a pharmaceutically acceptable anion, n=1 for doubly charged anions, n=2 for singly and triply charged anions. Also proposed is a method for obtaining a copper complex of the HAEE peptide, a pharmaceutical composition based on it and its use.

EFFECT: proposed copper complex is used to treat neurodegenerative diseases.

28 cl, 7 dwg, 5 tbl, 4 ex

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RU 2 784 732 C1

Authors

Kozin Sergej Aleksandrovich

Dates

2022-11-29Published

2022-07-15Filed