METHOD OF PREVENTION OF BLEEDING AND SPREADING OF METASTASES Russian patent published in 2019 - IPC A61B17/03 A61K31/10 A61K31/164 A61K31/245 A61K38/43 A61P7/04 A61P35/04 A61M5/178 A61M25/06 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to surgery and oncology, and can be used for the prevention of bleeding and metastasis in the radical surgical treatment of malignant neoplasms of the chest and abdominal cavity. For doing this determine the spinous process of the twelfth thoracic vertebra in the preoperative period in the sitting position of the patient, straightening. Stepping to the left of its spinous process by 2.5–3.0 cm, skin anesthesia and deeper-lying tissues are produced with a local anesthetic with a conventional injection needle. Further using a needle sort of Tuohy, moving the edges along the upper edge to the midline of the body, reach the transverse process of the twelfth thoracic vertebra. Bypass it laterally and from above, pushing the needle into the retroperitoneal space to the site of the formation of the thoracic lymphatic duct. Install the catheter. Further, in the preoperative stage, 40 minutes before the surgery, Lydazum 32 U, diluted in 2 ml of 0.25 % novocaine, is administered once through in-line catheter. Then after 5–10 minutes, 2 ml of Dicynone is administered once. After the next 5–10 minutes, 2 ml of Midodrine is administered once. Perform radical surgical treatment for malignant neoplasms. Perform lymphadenectomy. In the postoperative stage, Lydazum 32 U, diluted in 2 ml of 0.25 % novocaine, is administered 1 times a day through in-line catheter, on the 1st and 2nd days. Then after 5–10 minutes, 2 ml of Dicynone is administered. After 5–10 minutes, 2 ml of Midodrine is administered.

EFFECT: method provides an increase in the radicalism of surgical treatment and effective prevention of bleeding and spreading of metastases due to the lymphotropic administration of the hemostatic medication and adrenergic mimetic procedure in the retroperitoneal space to the site of formation of the thoracic lymphatic duct.

1 cl, 1 ex