METHOD OF COMBINATION TREATMENT OF LOCALLY ADVANCED NON-SMALL-CELL LUNG CANCER Russian patent published in 2012 - IPC A61N5/67 A61B17/00 A61K31/409 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, oncology, and can be used for combination treatment of locally advanced non-small-cell lung cancer. That is ensured by thorax computed tomography to determine an area of parietal and visceral pleura. It is attended by lung reduction with mediastinal lymph node dissection. That is accompanied with intraoperative photoradiation therapy. It is ensured by intravenous introduction of Photoditasine 0.8-1.0 mg/kg of body weight, In 2 hours, a lymph node dissection region, bronchial and vascular stumps are exposed to light stimuli generated by a diode laser at wave length 662 s and power density 40 J/cm² for a time estimated on account of the area of the lymph node dissection regions, the bronchial and vascular stumps. It is followed by light stimuli covering the parietal and visceral pleura at power density 4 J/cm² for a time estimated on account of the area of the bronchial and vascular stumps.

EFFECT: method provides improved therapeutic effects ensured by destruction of the lesions both within the lymph node dissection region, and on the periphery of the lung root reduction and tumour cell resorption in the operative wound, prevention of developing recurrent tumour growth within the pleural cavity.

6 cl, 2 dwg, 3 tbl, 2 ex