FIELD: chemistry.
SUBSTANCE: invention relates to a method for determining the amount of glycated haemoglobin (HbA1c) in a sample comprising hemolysis of erythrocytes in the sample to release HbA1c contained therein, contacting the released haemoglobin with a proteolytic agent to produce glycated haemoglobin decomposition products, determining the amount of HbA1c by quantifying the glycated haemoglobin decomposition products.
EFFECT: providing a method of determining the amount of glycated haemoglobin (HbA1c) in a sample and reagents which can be used in that respect, in which the chemical compounds essential to the reaction are present in sufficiently stable form.
15 cl, 6 ex, 8 tbl, 5 dwg
Title | Year | Author | Number |
---|---|---|---|
METHOD OF DETERMINATION OF GLYCOSYLATED HEMOGLOBIN IN THE PRESENCE OF NONGLYCOSYLATED HEMOGLOBIN, ANALYTICAL TEST KIT | 1990 |
|
RU2111494C1 |
METHOD AND COMPOSITION FOR DETERMINING GENERAL GLUCOSE CONTENTS IN THE WHOLE BLOOD | 1990 |
|
RU2050546C1 |
ANALYSIS AND QUANTITATIVE DETERMINATION OF GLYCATED HEMOGLOBINS BY CAPILLARY ELECTROPHORESIS, BUFFER COMPOSITIONS AND KITS FOR CAPILLARY ELECTROPHORESIS | 2010 |
|
RU2608911C2 |
METHOD FOR CLEANING FIBRINOGEN, FIBRINOGEN PRODUCT AND MEANS FOR CLEANING OR PRODUCING FIBRINOGEN PRODUCT | 2013 |
|
RU2663792C2 |
METHOD FOR FLUOROMETRIC DETERMINATION OF COPPER(II) IN SOLUTIONS | 2005 |
|
RU2295121C1 |
METHOD AND CELL FOR CARRYING OUT ANALYSIS | 2001 |
|
RU2247393C2 |
METHOD OF POTASSIUM ION CONCENTRATION ASSAY IN BIOLOGICAL MATERIAL | 1988 |
|
RU2054674C1 |
METHOD OF OBTAINING, METHOD OF PURIFICATION AND METHOD OF STABILISATION OF FACTOR VII, IX AND X POLYPEPTIDES | 2004 |
|
RU2364626C2 |
METHOD FOR ASSESSING LONG-TERM HYPERGLYCEMIA | 2013 |
|
RU2538715C1 |
METHOD OF DETERMINING POLYMER CONCENTRATION IN WATER SYSTEMS | 2008 |
|
RU2478950C2 |
Authors
Dates
2019-04-02—Published
2015-03-31—Filed