FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to hematology, and can be used for the targeted therapy of POEMS syndrome in severe form of Castleman disease. To do this, spend 2–10 courses of treatment, including intravenous administration of Bortezomib in the amount of 1.3 mg/m2 at 1, 4, 8 and 11 days of treatment with a 10-day break.
EFFECT: method allows to reduce the POEMS syndrome in patients with the plasma cell variant of Castleman disease due to the suppression of plasma cell proliferation when receiving a long-term remission of the disease and to improve the quality and longevity of patient life.
1 cl, 3 ex
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