FORMULATIONS OF AZAINDOLE COMPOUNDS Russian patent published in 2019 - IPC A61K31/506 A61K47/00 A61K9/20 A61K9/08 A61J3/10 A61P31/16 

Abstract RU 2685730 C1

FIELD: medicine; pharmaceuticals.

SUBSTANCE: pharmaceutical composition is intended for treating influenza A in a subject. Composition comprises: a) from 1 mg/ml to 20 mg/ml of compound (1) in water and b) 0.01 M to 0.1 M pharmaceutically acceptable pH modifier. Source of compound (1) is a crystalline salt of HCl compound (1) 1/2H2O, characterised by one or more peaks corresponding to 2-theta values measured in degrees, 10.5 ± 0.2, 5.2 ± 0.2, 7.4 ± 0.2 and 18.9 ± 0.2 on powder X-ray diffraction pattern. What is also disclosed is a method for producing a pharmaceutical composition. Each method for reducing the amount of influenza virus, inhibiting influenza virus replication and treating influenza independently uses such a pharmaceutical composition.

.

EFFECT: composition according to the invention is characterised by considerable efficacy in treating influenza A.

18 cl, 8 dwg, 29 tbl, 13 ex

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RU 2 685 730 C1

Authors

Simone Erik Artur

Sangkhvi Tapan

Banda Alamelu

Stavropoulos Ketrin

Dates

2019-04-23Published

2014-11-12Filed