METHOD OF PRODUCING ROD-SHAPED MAGNETITE NANOPARTICLES Russian patent published in 2019 - IPC C01G49/08 B01J19/12 B82B3/00 B82Y30/00 B82Y5/00 A61P35/00 A61K33/26 A61K41/00 A61K49/06 

FIELD: medicine.

SUBSTANCE: invention can be used in biomedicine for the diagnosis and treatment of malignant tumors. Method for producing rod-shaped magnetite nanoparticles involves preparing an aqueous suspension of a precursor, which is a rod of nanoparticles of akagenit, to which a solution of a reducing agent is added, which is a compound from the group of hydrazines with two free electrons. Specified solution of the reducing agent is added in an amount to ensure the reduction of iron Fe³⁺ to Fe²⁺ in alkaline conditions, characterized by pH 10–14. Resulting solution is irradiated with microwave radiation at 200±10 W and 90–100 °C for 30±2 sec. Reaction mass is cooled to room temperature. Resulting product is washed with deionized water to remove unreacted substances and dispersed in deionized water at neutral pH.

EFFECT: invention allows to obtain rod-shaped magnetite nanoparticles with stability in aqueous solutions under physiological conditions and a narrow size distribution of nanoparticles ±10 nm, reduce the time of the process.

6 cl, 5 dwg, 3 tbl, 4 ex