FIELD: chemistry.
SUBSTANCE: invention relates to the BRAF kinase inhibitor, which is the compound of N-(3-(5-(4-chlorophenyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propant-1-sulfonamide of formula 1.
1.
EFFECT: proposed is remedy for characterized by the BRAF kinase mutation proliferative disease, preferably melanoma, prevention or treatment.
1 cl, 2 dwg, 2 tbl, 4 ex
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N-(3-(5-(4-CHLOROPHENYL)-1N-PYRAZOLO[3,4-B]PYRIDINE-3-CARBONYL)-2,4-DIFLUOROPHENYL)PROPANE-1-SULPHONAMIDE CRYSTALLINE FORM, ACTIVE COMPONENT, PHARMACEUTICAL COMPOSITION AND MEDICINE | 2018 |
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Authors
Dates
2019-05-07—Published
2018-06-18—Filed