FIELD: chemistry.
SUBSTANCE: invention relates to the field of organic chemistry, namely to N-(3-(5-(4-chlorophenyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propan-1-sulfonamide of formula 1 or its pharmaceutically acceptable salt. Invention also relates to a new crystalline form, an active component, a pharmaceutical composition and a drug based on compound 1.
1.
EFFECT: new compound is obtained for the prevention or treatment of proliferative diseases, characterized by BRAF kinase mutation.
10 cl, 4 dwg, 5 tbl, 10 ex
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Authors
Dates
2019-01-29—Published
2018-06-01—Filed