METHOD FOR DETECTING PERIVESICAL FIBRE INVASION IN BLADDER CANCER USING DYNAMIC MAGNETIC RESONANCE CYSTOGRAPHY Russian patent published in 2019 - IPC A61B5/55 A61M25/01 

FIELD: medicine.

SUBSTANCE: invention relates to oncology, urology and radiation diagnosis, and can be used to detect perivestic carbolic tissue invasion in bladder cancer using dynamic magnetic resonance cystography. Bladder is pre-catheterised. Dynamic magnetic resonance cystography is performed on a high-field magnetic resonance tomograph. Performing a series of scanning in three planes in T2 mode for 10–20 seconds each. That is followed by a fractional introduction through the catheter into the bladder of physiologic saline or furacilin, warmed to body temperature, each time in amount of 20 ml, until the bladder completely spreads and urinating urination. On the obtained images, a tumour is detected in the form of areas of thickening of the bladder wall and exophytic formations, the elasticity of the affected wall and degree of rigidity are evaluated. Further, post-processing processing of the obtained images is used, which includes selecting at least six ROI interest zones in the perivesical tissue along the wall contour in the cross-section through the tumour centre, their comparison by the MP-signal intensity diagram in the wall expansion dynamics and colour mapping of wall displacement. Post-processing processing of the obtained images and the intensity of the MP signal over a period of less than 10 %, which corresponds to the stable MP signal, enables diagnosing infiltration of periesical cellular tissue with a tumour. Post-processing of the obtained images and changing intensity of the MP signal for 10 % and more, which corresponds to an unstable MP signal, diagnose the absence of perivesical fibre infiltration.

EFFECT: method provides higher accuracy of diagnosing staging of urinary bladder cancer by performing dynamic magnetic resonance cystography on a high-field magnetic resonance tomograph, post-processing of the obtained images and establishing a change in intensity of the MP signal over time.

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