FIELD: biochemistry.
SUBSTANCE: invention relates to biochemistry. Described is a group of inventions comprising an isolated antibody which specifically binds to HPA-1a, a nucleic acid molecule encoding said antibody, a composition for binding HPA-1a, a method of producing an antibody, a method of detecting HPA-1a, comprising bringing the composition into contact with an antibody, an analysis method for determining the presence or absence of HPA-1a in a sample, using the above antibody as a reference standard for quantitative assessment of antibodies to HPA-1a in a sample, method for treating or preventing fetus and newborn alloimmune thrombocytopenia (FNAIT), using said antibody in preparing a drug for treating or preventing FNAIT.
EFFECT: invention extends the range of products for binding with HPA-1a.
25 cl, 14 dwg, 4 tbl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
ANTI-INTEGRIN ALPHA-2 ANTIBODIES AND USING THEM | 2011 |
|
RU2545401C2 |
PEPTIDE OR PEPTIDE COMPLEX BINDING TO alpha2- INTEGRIN, METHODS FOR PRODUCTION AND USE THEREOF | 2011 |
|
RU2588668C2 |
COMBINED THERAPY FOR CANCER TREATMENT | 2016 |
|
RU2731202C2 |
ALPHA5-BETA 1 ANTIBODIES AND USING THEM | 2009 |
|
RU2528736C2 |
ANTI-SIRPα ANTIBODY AND USE THEREOF | 2021 |
|
RU2822496C1 |
THERAPEUTIC BINDING MOLECULES | 2002 |
|
RU2328506C2 |
PROTEIN BOUND WITH HUMAN GLYCOPROTEIN, COMPOSITION, PHARMACEUTICAL COMPOSITION, EXPRESSION VECTOR | 2016 |
|
RU2773819C2 |
ANTI-αvβ8 ANTIBODIES AND COMPOSITIONS AND THEIR USE | 2019 |
|
RU2812478C2 |
CHIMERIC AND HUMANISED INTEGRIN α5β1 ANTIBODIES MODULATING ANGIOGENESIS | 2003 |
|
RU2346701C2 |
ANTI-OSTEOPANTINE RECOMBINANT ANTIBODY AND USES THEREOF | 2002 |
|
RU2305111C2 |
Authors
Dates
2019-05-22—Published
2015-03-31—Filed