ANTIBODIES TO HPA-1a Russian patent published in 2019 - IPC C07K16/28 A61K39/00 A61K39/395 A61K39/42 

Abstract RU 2688627 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to biochemistry. Described is a group of inventions comprising an isolated antibody which specifically binds to HPA-1a, a nucleic acid molecule encoding said antibody, a composition for binding HPA-1a, a method of producing an antibody, a method of detecting HPA-1a, comprising bringing the composition into contact with an antibody, an analysis method for determining the presence or absence of HPA-1a in a sample, using the above antibody as a reference standard for quantitative assessment of antibodies to HPA-1a in a sample, method for treating or preventing fetus and newborn alloimmune thrombocytopenia (FNAIT), using said antibody in preparing a drug for treating or preventing FNAIT.

EFFECT: invention extends the range of products for binding with HPA-1a.

25 cl, 14 dwg, 4 tbl, 4 ex

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Authors

Mikaelsen Tere

Ile Ejstejn

Stuge Tor Bryunyar

Khusebekk Anne

Tiller Khejdi

Eksteen Mariana

Skogen Bern Ragnar

Dates

2019-05-22Published

2015-03-31Filed