FIELD: medicine.
SUBSTANCE: venous blood is sampled; DNA is recovered, and +1931 A/T MIP-1β locus allele carriage state is detected. If the +1931T MIP-1β allele is detected, a cyclophosphamide therapy is recommended, and if the +1931A MIP-1β allele is found, the cyclophosphamide therapy appears to be ineffective.
EFFECT: method enables predicting the clinical effectiveness before the beginning of the therapy a possibility to detect the patients who are not recommended to get the cyclophosphamide therapy, and those who are recommended to indicate the cyclophosphamide therapy notwithstanding a number of potential side effects of the preparation.
2 dwg, 2 tbl, 1 ex
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