METHOD FOR PREDICTING THE RISK OF DEVELOPING ISCHEMIC HEART DISEASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS COMBINED WITH SUBCLINICAL HYPOTHYROIDISM Russian patent published in 2019 - IPC G01N33/48 

Abstract RU 2691937 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to a method for prediction of a risk of developing ischemic heart disease (IHD) in patients with type 2 diabetes mellitus combined with subclinical hypothyroidism, consisting in the fact that venous blood is used to determine levels of the vascular endothelium adhesion molecule of 1 type – VCAM1, glycated hemoglobin – HbA1c, antibodies to thyreperoxidase – AbTPO, as well as patient's age and calculating an I – risk index of developing IHD by formula: I=(-2.36145+0.41297⋅VCAM1+0.225285⋅HbA1c+0.096089⋅A-0.091315⋅AbTPO)/730, where: VCAM1 is level adhesion molecule of vascular endothelium of 1 type, ng/ml; HbA1c – plasma glucose level for 3 months, %; A is age, years; AbTPO – level of antibodies to thyreperoxidase, mcME/ml; and if the I value is less than 0.69, a low risk is predicted IHD, at I 0.70 to 0.80 high risk is predicted IHD, with I above 0.81 IHD already exists.

EFFECT: invention provides more effective prediction of developmental risk IHD in patients with type 2 diabetes mellitus with subclinical hypothyroidism.

1 cl, 4 tbl, 3 ex

Similar patents RU2691937C1

Title Year Author Number
METHOD FOR PREDICTION OF THE RISK OF DEVELOPING ISCHEMIC HEART DISEASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS COMBINED WITH SUBCLINICAL THYROTOXICOSIS 2018
  • Kasatkina Svetlana Grigorevna
  • Panova Tamara Nikolaevna
  • Shvarts Roman Nikolaevich
  • Kasatkina Oksana Sergeevna
RU2691620C1
METHOD FOR PREDICTING THE RISK OF DEVELOPING LIFE-THREATENING VENTRICULAR ARRHYTHMIAS IN WOMEN WITH CORONARY HEART DISEASE IN COMBINATION WITH TYPE 2 DIABETES MELLITUS AND HYPOTHYROIDISM 2017
  • Fedorova Alena Petrovna
  • Serebryakova Olga Vladimirovna
  • Serkin Dmitrij Mikhajlovich
  • Serebryakova Nataliya Alekseevna
RU2663630C1
METHOD FOR PREDICTION OF RISK OF CARDIOVASCULAR DISEASES IN PATIENTS WITH NEUROCIRCULATORY DYSTONIA WITH SIGNS OF CONNECTIVE TISSUE DYSPLASIA 2014
  • Demidova Lidiya Alekseevna
  • Panova Tamara Nikolaevna
  • Shvarts Roman Nikolaevich
RU2597797C2
METHOD OF PREDICTING THE RISK OF MYOCARDIAL INFARCTION IN PATIENTS WITH COMORBID PATHOLOGY - TYPE 2 DIABETES MELLITUS, CHRONIC KIDNEY DISEASE AND HYPOTHYROIDISM 2022
  • Soloveva Aleksandra Viktorovna
  • Berstneva Svetlana Viacheslavovna
  • Berstneva Svetlana Vyacheslavovna
RU2802420C1
METHOD FOR DETERMINING RISK OF CORONARY ARTERY ATHEROSCLEROSIS IN PATIENTS SUFFERING FROM DIABETES MELLITUS ACCOMPANIED BY CARDIOVASCULAR DISORDERS 2013
  • Tatarchenko Ivan Porfir'Evich
  • Pozdnjakova Nadezhda Viktorovna
  • Mordovina Alla Gennad'Evna
  • Morozova Ol'Ga Ivanovna
RU2532521C1
METHOD FOR PREDICTING ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH CORONARY HEART DISEASE 2017
  • Sergeeva Elena Gennadievna
RU2682811C1
METHOD FOR FORECASTING THE ONE-YEAR RISK OF DEVELOPMENT OF ADVERSE CARDIOVASCULAR EVENTS AFTER STENTING OF CORONARY ARTERIES IN PATIENTS WITH CORONARY HEART DISEASE WITH METABOLIC SYNDROME WITHOUT INSULIN RESISTANCE 2017
  • Teplyakov Aleksandr Trofimovich
  • Grakova Elena Viktorovna
  • Svarovskaya Alla Vladimirovna
  • Suslova Tatyana Evgenevna
  • Lavrov Aleksej Gennadevich
RU2663496C1
METHOD OF PREDICTING RISK OF DEVELOPMENT OF ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH CORONARY HEART DISEASE AND TYPE 2 DIABETES WITH PRIOR CORONARY ARTERY STENTING 2015
  • Tepljakov Aleksandr Trofimovich
  • Kuznetsova Alla Vladimirovna
  • Grakova Elena Viktorovna
  • Protopopova Natalja Vsevolodovna
  • Andrijanova Anna Vladimirovna
  • Suslova Tatjana Evgenevna
RU2582291C1
METHOD FOR PREDICTING THE RISK OF DEVELOPING ISCHEMIC HEART DISEASE IN MEN WITH TYPE 2 DIABETES MELLITUS BASED ON GENOTYPING POLYMORPHISM rs16931366 OF ITPR2 GENE 2024
  • Azarova Iuliia Eduardovna
  • Postnikova Mariia Igorevna
  • Azarova Valentina Alekseevna
  • Klesova Elena Iurevna
  • Mikhin Vadim Petrovich
  • Polonikov Aleksei Valerevich
RU2821764C1
METHOD FOR PREDICTING RISK OF DEVELOPING CARDIOVASCULAR COMPLICATIONS IN PATIENTS WITH STABLE ISCHEMIC HEART DISEASE, HAVING UNDERGONE PLANNED ENDOVASCULAR MYOCARDIAL REVASCULARIZATION 2021
  • Svarovskaia Alla Vladimirovna
  • Arzhanik Marina Borisovna
  • Garganeeva Alla Anatolevna
RU2770273C1

RU 2 691 937 C1

Authors

Kasatkina Svetlana Grigorevna

Panova Tamara Nikolaevna

Shvarts Roman Nikolaevich

Kasatkina Oksana Sergeevna

Dates

2019-06-19Published

2018-11-26Filed