METHOD FOR PREDICTING THE RISK OF DEVELOPING ISCHEMIC HEART DISEASE IN MEN WITH TYPE 2 DIABETES MELLITUS BASED ON GENOTYPING POLYMORPHISM rs16931366 OF ITPR2 GENE Russian patent published in 2024 - IPC G01N33/58 C12Q1/6806 C12Q1/6827 C12Q1/686 C12Q1/6876 C12Q1/6883 G16H50/30 

Abstract RU 2821764 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to medical diagnostics, and can be used to predict the risk of developing ischemic heart disease in males with type 2 diabetes mellitus. Sample of peripheral venous blood is sampled and DNA is extracted. Polymorphic variant rs16931366 (A>C) of the ITPR2 gene is analysed. If the genotype rs16931366-C/C is detected, an increased risk of ischemic heart disease is predicted in Central Russian males suffering type 2 diabetes mellitus. If observing the genotype rs16931366-A/A or rs16931366-A/C, a low risk is predicted.

EFFECT: method provides obtaining new criteria for assessing the risk of ischemic heart disease in men of Central Russia with type 2 diabetes mellitus according to the genetic polymorphism rs16931366 (A>C) of the ITPR2 gene.

1 cl, 1 tbl, 3 ex

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RU 2 821 764 C1

Authors

Azarova Iuliia Eduardovna

Postnikova Mariia Igorevna

Azarova Valentina Alekseevna

Klesova Elena Iurevna

Mikhin Vadim Petrovich

Polonikov Aleksei Valerevich

Dates

2024-06-26Published

2024-01-26Filed