HYDROGEL MATERIAL BASED ON A SALT OF A CHITOSAN-CONTAINING SUBSTANCE AND A METHOD FOR PRODUCTION THEREOF Russian patent published in 2019 - IPC A61L15/28 A61K9/00 A61K31/722 C08L5/00 

FIELD: medicine; biotechnology.

SUBSTANCE: group of inventions refers to medicine, biotechnology, cosmetology and pharmaceutical industry, specifically to production of a therapeutic and preventive hydrogel material based on a salt of a chitosan-containing substance with intrinsic biological activity, having antibacterial, anti-inflammatory and wound-healing action, which can be used for care and treatment of various types of wounds, ulcers, bedsores and burns, age and mimic wrinkles, nutrition and moistening of the epidermis, for delivery of drugs and other biologically active compounds (topically, transdermally, through the mucosa), as well as in biotechnology for producing matrices for growing cell cultures. Hydrogel material contains a salt of a chitosan-containing substance, an organic acid, polyvinyl alcohol, silicon polyolates, glycerine and water. Method of producing hydrogel material involves dissolving the chitosan-containing substance in an aqueous solution of organic acid, adding polyvinyl alcohol into the mixture, then adding the silicon glycerolate solution in glycerine, obtained mixture is pouring into the mold and holding it until a film-like structure is obtained.

EFFECT: creation of efficient, high-quality hydrogel material based on a salt of a chitosan-containing substance, which can be applied in the form of monolithic, elastic and high congruent (to surface with complex relief) of glycero-hydrogel plate, and having its own biological activity, antibacterial, anti-inflammatory and wound-healing action.

8 cl, 30 ex, 3 dwg, 4 tbl