FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, specifically to pharmacology, and can be used to produce xyloglucan hydrogels, where xyloglucan has a degree of degalactosation of 44 or 45 %, also containing fibroblast growth factor compound 18 (FGF-18), for intraarticular administration. Hydrogels can be used, after formation in situ from a liquid form, for treating cartilage tissue diseases, such as osteoarthritis or cartilage tissue injury.
EFFECT: group of inventions enables effective treatment of cartilage tissue by converting liquid composition into gel after introduction into human body with preservation of its bioactivity.
8 cl, 17 dwg, 5 tbl, 9 ex
| Title | Year | Author | Number |
|---|---|---|---|
| FGF-18 COMPOSITION IN ALGINATE/COLLAGEN HYDROGELS | 2014 |
|
RU2698210C2 |
| CHITOSAN COMPOSITION | 2008 |
|
RU2482133C2 |
| DELAYED-RELEASE DELIVERY SYSTEMS CONTAINING TRACELESS LINKERS | 2018 |
|
RU2772690C2 |
| NEUROENDOCRINE FACTORS FOR TREATING DEGENERATIVE DISORDERS | 2008 |
|
RU2496790C2 |
| STRUCTURES OF FUSION PROTEIN IN SPIDER SILK FOR BINDING TO ORGANIC TARGET | 2011 |
|
RU2624036C2 |
| HYBRIDOMA DESIGNATES AS 199M AND MONOCLONAL ANTIBODY SECRETED BY THIS HYBRIDOMA | 1997 |
|
RU2183671C2 |
| MONOCLONAL ANTIBODY, WHICH HAS IMMUNOSUPRESSIVE ACTIVITY, OR ITS ANTIGEN-BINDING FRAGMENT | 2011 |
|
RU2559550C2 |
| PEPTIDE STIMULATING FORMATION OF SPECIFIC ANTIBODIES AGAINST OLIGOMERIC FORM OF NUCLEOPHOSMIN IN TUMOUR CELLS | 2009 |
|
RU2401275C1 |
| METHOD FOR PURIFICATION OF DOUBLE-STRANDED DNA MOLECULE, BACKING FOR ITS REALIZATION AND METHOD FOR PREPARING SUPPORT | 2001 |
|
RU2315104C2 |
| COMPOSITION INCLUDING EXOSOME OBTAINED FROM STEM CELLS FOR INDUCTION OF ADIPOGENIC DIFFERENTIATION, REGENERATION OF FAT TISSUE, SKIN WHITENING OR CORRECTION OF WRINKLES | 2021 |
|
RU2759508C1 |
