FIELD: chemistry.
SUBSTANCE: disclosed are prodrugs of NMDA antagonist, (S)-1-phenyl-2-(pyridin-2-yl)ethanamine of formula (I):
where R1 is
AA is a peptide bond-bound natural amino acid; or a pharmaceutically acceptable salt thereof.
EFFECT: prodrugs disclosed are useful for treating depression (particularly, major depressive disorder) or pain.
15 cl, 1 dwg, 5 tbl, 18 ex
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