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2 695 661

(13)

(51)

IPC

A61K36/76(2006-01-01)

B01D11/02(2006-01-01)

A61K127/00(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2019112565, 2019-04-24

(24)

Start date

2019-04-24

(22)

Actual filing date

2019-04-24

(45)

Published

2019-07-25

(72)

Inventor

Kurkin Vladimir AleksandrovichKupriyanova Elena AleksandrovnaRyzhov Vitalij MikhajlovichLyamin Artem ViktorovichKondratenko Olga Vladimirovna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

METHOD FOR PRODUCTION OF BLACK POPLAR LEAF INFUSION HAVING ACTIVITY WITH RESPECT TO BURKHOLDERIA STRAINS Russian patent published in 2019 - IPC A61K36/76 B01D11/02 A61K127/00 A61P31/04

Abstract RU 2695661 C1

FIELD: pharmaceutics.

SUBSTANCE: invention relates to pharmaceutical industry, specifically to a method for producing black poplar leaves, having inhibitory activity on Burkholderia strains. Method for producing black poplar leaf extracts, having inhibitory activity on Burkholderia strains, in which poplar leaves are infused with 70 % ethyl alcohol in ratio "raw material – extractant" 1:8 under conditions of fractional extraction – twice at room temperature for 24 hours with subsequent extraction at heating on a boiling water bath and combination of three extracts; in result is produced ready combined product – black poplar leaves infusion on 70 % ethyl alcohol, wherein the content of the sum of flavonoids (target substances) determined using a spectrophotometric method is 0.51 %, the output of the desired substances in tincture is 90.0 %.

EFFECT: method described above enables to obtain an agent with pronounced inhibitory activity on Burkholderia strains.

1 cl, 1 tbl, 1 ex

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RU 2 695 661 C1

Authors

Kurkin Vladimir Aleksandrovich

Kupriyanova Elena Aleksandrovna

Ryzhov Vitalij Mikhajlovich

Lyamin Artem Viktorovich

Kondratenko Olga Vladimirovna

Dates

2019-07-25—Published

2019-04-24—Filed