FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention relates to a complex of sitagliptin tannate, in which the ratio of sitagliptin to tannic acid is approximately 1:2 by weight. Invention also refers to a pharmaceutical composition and to an oral dosage form.
EFFECT: technical result is obtaining sitagliptin tantalum complex with a pleasant taste and having a low release rate at neutral pH and immediate release at acidic pH, that enables to create an oral dosage form with a pleasant taste, which is easier to swallow, which improves patient compliance with the therapeutic regimen when taking the drug.
7 cl, 3 dwg, 2 ex
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