FIELD: pharmacology.
SUBSTANCE: group of inventions can be used for the application of the IBAT inhibitor and the bile acid binder (cholestyramine, colestipol, or colesevelam) for preparing the combination for simultaneous, sequential or separate introduction in the treatment of the liver diseases. Herewith the bile acid binder is located in the core and is composed for release in the colon, and the IBAT-inhibitor is located in the outer layer, composed for immediate or delayed release in the distal jejunum or in the proximal ileum. Also the use of the pharmaceutical composition is provided, comprising an IBAT-inhibitor and a bile acid binder for preparing the medicine for the treatment of the liver diseases.
EFFECT: group of inventions provides treatment of the liver diseases.
14 cl, 2 tbl, 20 ex
| Title |
Year |
Author |
Number |
| IBAT INHIBITOR FOR TREATING HEPATIC DISORDERS |
2011 |
- Jillberg Per-Jeran
- Graffner Khans
- Starke Ingemar
|
RU2591188C2 |
| BENZOTHIADIAZEPINE DERIVATIVES AND METHOD FOR PRODUCTION THEREOF (VARIANTS) |
2002 |
- Starke Ingemar
- Dal'Strum Mikaehl' Ul'F Jukhan
- Blumberg David
- Alenfal'K Suzanne
- Sharet Ture
- Lemurell' Malin
|
RU2305681C2 |
| USE OF IBAT INHIBITOR FOR TREATING AND PREVENTING CONSTIPATION |
2008 |
- Abrakhamsson Khasse Roland
- Gillberg Per-Goran
|
RU2482850C2 |
| IBAT ANTIOXIDANT APPLICATION FOR TREATMENT OR PREVENTION OF COPROSTASIA |
2004 |
- Abrakhamsson Khasse Roland
- Gillberg Per-Goran
|
RU2342928C2 |
| BENZOTHIADIAZEPINE DERIVATIVES, METHOD OF THEIR OBTAINING AND APPLICATION, PHARMACEUTICAL COMPOSITION WITH INHIBITION EFFECT ON ILEUM BILE ACID TRANSFER |
2003 |
- Ingemar Starke
- Mikaehl' Ul'F Jokhan Dal'Strum
- Mats Peter Nordberg
- Sjuzanna Alenfal'K
- Andreas Krister Vall'Berg
- Stig Jonas Bostrum
|
RU2333205C2 |
| METHODS FOR INCREASING HEIGHT OF PEDIATRIC PATIENTS WITH CHOLESTATIC LIVER DISEASE |
2020 |
- Jaecklin, Thomas
- Dorenbaum, Alejandro
|
RU2822484C2 |
| DERIVATIVES OF PEPTIDES COMPRISING THIAZEPINE GROUP FOR TREATMENT OF HYPERGLYCEMIC STATES |
2003 |
- Starke Ingemar
- Dal'Strom Mikaehl' Ul'F Jokhan
- Alenfal'K Susanna
- Sk'Jaret Ture
- Lemurell' Malin
|
RU2315772C2 |
| 1,5-BENZOTHIAZEPINES AND EMPLOYMENT THEREOF AS ANTIHYPERLIPIDEMIC DRUGS |
2001 |
- Starke Ingemar
- Dal'Strom Mikaehl'
- Blomberg David
|
RU2302414C2 |
| DERIVATIVES OF SUBSTITUTED PHENYLPROPIONIC ACID AS AGONISTS OF HUMAN ALPHA-RECEPTORS ACTIVATED BY PEROXISOME PROLIFERATOR (PPARα), METHOD AND INTERMEDIATE COMPOUNDS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF, THEIR USING AND METHODS FOR TREATMENT OF DYSLIPIDEMIA IN DIABETES MELLITUS TYPE 2 |
2002 |
- Al'Stermark Lindstedt Ehva-Lotte
- Ol'Sson Anna Kristina
- Li Lanna
|
RU2303031C2 |
| DERIVATIVES OF SUBSTITUTED PHENYLPROPIONIC ACID AS AGONISTS OF HUMAN ALPHA-RECEPTOR (PPARα) ACTIVATED BY PEROXISOME PROLIFERATORS, METHOD AND INTERMEDIATE COMPOUNDS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF, THEIR USING AND METHODS FOR DYSLIPIDEMIA TREATMENT AND TYPE 2 DIABETES MELLITUS |
2002 |
- Al'Stermark Lindstedt Ehva-Lotte
- Ol'Sson Anna Kristina
- Li Lanna
|
RU2300517C2 |
