FIELD: chemistry.
SUBSTANCE: invention relates to 1,7,7-trimethylbicyclo[2.2.1]heptane-2-yl 3-(piperidin-1-yl)propionate hydrochloride compound of formula I
,
in which biological activity is detected, which consists in inhibiting virus reproduction Ebola. This compound I is proposed to be used as an Ebola virus reproduction inhibitor, which can be used in medicine, virology and pharmacology.
EFFECT: higher effectiveness of Ebola virus reproduction suppression in comparison with the prototype compound and wider range of the viruses reproduction inhibitors.
1 cl, 1 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 3-N-SUBSTITUTED BORNYL PROPIONATES USED AS MARBURG VIRUS INHIBITORS | 2017 |
|
RU2649406C1 |
| N-HETEROCYCLIC BORNYL AMINE DERIVATIVES AS ORTHOPOXVIRUS INHIBITORS | 2018 |
|
RU2687254C1 |
| APPLICATION OF ALIPHATIC IMINO-DERIVATIVES OF CAMPFOR AS EFFECTIVE INHIBITORS OF REPRODUCTION OF INFLUENZA VIRUS STRAIN A/CALIFORNIA/07/09 (H1N1) PDM09 AND A/PUERTO RICO/8/34 (H1N1) | 2016 |
|
RU2651754C1 |
| IMINE COMPOUNDS OF CAMPHOR - EFFECTIVE INHIBITORS OF REPRODUCTION OF FLU VIRUS (A/California/07/09 (H1N1)pdm09 STRAIN) | 2014 |
|
RU2554934C1 |
| IMINE DERIVATIVES OF CAMPHOR, CONTAINING AROMATIC OR HETEROAROMATIC FRAGMENT - INHIBITORS OF REPRODUCTION OF FLU VIRUS (STRAIN A/CALIFORNIA/07/09(H1N1)pdm09) | 2015 |
|
RU2607451C1 |
| N-BORNIL- AND N-PHENCHYLCARBOXAMIDES USED AS ORTHOPOXVIRUS REPLICATION INHIBITORS | 2022 |
|
RU2800448C1 |
| FENCHONE N-ACYLHYDRAZONE WITH AN EPOXY ISOINDOLE FRAGMENT USED AS AN INHIBITOR OF HANTAAN VIRUS REPRODUCTION | 2020 |
|
RU2733472C1 |
| CHIRAL ZINC COMPLEXES WITH ETHYLENEDIAMINE TERPENE DERIVATIVES | 2022 |
|
RU2785281C1 |
| (1S,3aR,4R,7aS)-N-(2,2,4,7a-TETRAMETHYLOCTAHYDRO-1,4-ETHANOINDENE-3a-YL)-ACETAMIDE APPLICATION AS A INFLUENZA VIRUS REPRODUCTION INHIBITOR | 2016 |
|
RU2616255C1 |
| O-ACYLAMIDOXIMES AND 1,2,4-OXADIAZOLES CONTAINING A FRAGMENT OF BICYCLO[2.2.1]HEPTANONE-2 AS INHIBITORS OF THE REPRODUCTION OF PHYLOGENETICALLY DIFFERENT INFLUENZA A VIRUSES: STRAINS A/PUERTO RICO/8/34 (H1N1), A/ANHUI/1/2013 (H7N9) | 2022 |
|
RU2798171C1 |
