FIELD: medicine; pharmaceuticals.
SUBSTANCE: use of O-acylamidoximes and 3,5-disubstituted-1,2,4-oxadiazoles of general formulas I and II, respectively, as inhibitors of the reproduction of influenza A virus, such as strain A/Anhui/1/2013 (H7N9), is proposed.
EFFECT: compounds exhibit a high degree of suppression of influenza virus replication in MDCK cell culture.
1 cl, 1 dwg, 2 tbl, 28 ex
I d, g II c, d, i
R = d) 3-FC6H4, g) 4-BrC6H4, с) 4-FC6H4, i) 4-ClC6H4CH2-.
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