FIELD: medicine.
SUBSTANCE: invention can be used for application of a lidocaine derivative - N-acetyl-L-glutamate 2-diethylamino-21,61-dimethyl phenylacetamide of the general formula (1)
with local anesthetic activity, for terminal anesthesia.
EFFECT: invention allows to reduce acute toxicity, increase the breadth of therapeutic action, increase the depth and duration of terminal local anesthesia without a local irritant effect compared to lidocaine.
3 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| APPLICATION OF 2,6-DIMETHYLPHENYLACETAMIDE DERIVATIVES WITH LOCAL ANESTHETIC ACTIVITY FOR INFILTRATION AND CONDUCTION ANESTHESIA | 2017 |
|
RU2657613C1 |
| METHOD OF PRODUCING A 2,6-DIMETHYLPHENYLACETAMIDE DERIVATIVE HAVING CEREBROPROTECTIVE ACTIVITY | 2018 |
|
RU2690506C1 |
| PHARMACEUTICAL COMPOSITION WITH ANTIARRHYTHMIC ACTIVITY OF VARIOUS ETIOLOGIES | 2021 |
|
RU2783944C1 |
| 2-(DIETHYLAMINO)-N-(2,6-DIMETHYLPHENYL)ACETAMIDE L-GLUTAMATE, HAVING PROLONGED ANTIARRHYTHMIC ACTIVITY, PHARMACEUTICAL COMPOSITION | 2018 |
|
RU2697717C1 |
| 1-(2-TERT-BUTYLAMINOETHYL)-2-TERT-BUTLAMIDAZO (1,2-a)BENZIMIDAZOLE DIHYDROCHLORIDE HAVING LOCALLY ANESTHETIC ACTIVITY | 2000 |
|
RU2160263C1 |
| 4-HYDROXY-3-[N-(PHENACYL)BENZYLAMINO]-N-BENZYLBUTAMIDE HYDROBROMIC SALT SHOWING LOCAL ANESTHETIZING ACTIVITY | 1989 |
|
SU1713242A1 |
| 3-BENZYLAMINO-4-HYDROXY-N-BENZYLBUTANEAMIDE HEMIGLUTARATE SHOWING LOCAL ANESTHETIZING ACTIVITY | 1989 |
|
SU1663928A1 |
| DERIVATIVES OF 2-DIETHYLAMINO-2,6-DIMETHYLPHENYLACETAMIDE ELICITING ANTI-ARRHYTHMIC ACTIVITY | 2002 |
|
RU2223263C1 |
| 2-TERT-BUTYL-1-(3-DIETHYLAMINOPROPYL)IMIDAZO [1,2-A] BENZIMIDAZOLE DIHYDROCHLORIDE HAVING LOCALLY ANESTHETIC AND ANTIARRHYTHMIC ACTIVITY | 2000 |
|
RU2160262C1 |
| 1-(2-DIETHYLAMINOETHYL)-2-PHENYLIMIDAZO[1,2-A]BENZIMIDAZOLE DIHYDROCHLORIDE POSSESSING TOPICAL ANESTHETIC EFFECT AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 2006 |
|
RU2314312C1 |
