AFUCOSYLATED FGFR2IIIB FIBROBLAST GROWTH FACTOR RECEPTOR Russian patent published in 2019 - IPC C07K16/28 C12N15/13 C12N15/63 A61K39/00 

Abstract RU 2698061 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to biochemistry, particularly a composition for treating cancer, wherein cancer involves a solid tumour that overexpresses FGFR2IIIb. Disclosed is afucosylated FGFR2IIIb antibody, a host cell for expression of said antibody. Disclosed is a method of producing said antibody, a method of treating cancer using said antibody.

EFFECT: invention has the ability effectively treat cancer associated with overexpression of FGFR2IIIb.

77 cl, 11 dwg, 4 tbl, 6 ex

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RU 2 698 061 C2

Authors

Kharding Tomas

Pirs Kristen

Patil Namrata

Brennan Tomas

Khamblton Dzhuli

Dates

2019-08-21Published

2014-07-31Filed