NOVEL ANTI-FGFR2B ANTIBODIES Russian patent published in 2025 - IPC C07K16/28 A61K39/395 G01N33/574 A61P35/00 

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, in particular to an isolated antibody or an antigen-binding fragment thereof capable of specifically binding to both fibroblast growth factor receptor 2b (FGFR2b), and with FGFR1b, a method for production thereof, as well as to a conjugate and compositions containing same. Also disclosed is an isolated polynucleotide encoding said antibody or a fragment thereof, as well as a host cell and a vector containing same. Invention also relates to a method for diagnosing a disease or condition associated with FGFR2b and/or FGFR1b, a method for detecting the presence or amount of FGFR2b and/or FGFR1b in a sample, as well as to a method for the prediction of a disease or condition associated with FGFR2b and/or FGFR1b in a subject, comprising the use of said antibody or fragment thereof.

EFFECT: invention is effective for treating a disease or condition associated with FGFR2b and/or FGFR1b.

40 cl, 8 dwg, 3 tbl, 7 ex