FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine and concerns an immunogenic composition containing an antigen component and an adjuvant component. A) adjuvant component contains an emulsion containing oil, an immunostimulating oligonucleotide containing CpG, and diethylaminoethyl (DEAE)-dextran and b) the antigen component contains 0.5–10 mcg of the FMD virus (foot-and-mouth disease) composition per dose. Also disclosed are a method of treating or preventing FMD-induced damages in an animal, a method for keeping a herd and a method of reducing the frequency of FMD persistence in a ruminant.
EFFECT: group of inventions provides 100 % effective protection of ruminant against foot-and-mouth disease using said composition containing a low amount of the antigen component of the FMD virus per dose.
29 cl, 1 dwg, 8 tbl, 2 ex
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Authors
Dates
2019-08-26—Published
2016-01-15—Filed