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(19)

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2 730 011

(13)

(51)

IPC

A61K39/39(2006-01-01)

A61K9/107(2006-01-01)

A61P1/00(2006-01-01)

(21) (22)

Application

2016109925, 2014-09-19

(24)

Start date

2014-09-19

(22)

Actual filing date

2014-09-19

(45)

Published

2020-08-14

(72)

Inventor

Dominowski Paul JosephWilmes LaurenFoss Dennis L.Mohr KaoriGallo GuillermoHardham John MorganKrebs Richard LeeLightle Sandra Ann MarieMahan SumanMediratta SangitaMwangi DuncanRai Sharath K.Salmon Sarah A.Vora ShaunakFontaine Michael ChristopherSmith David George EmslieFitzpatrick Julie LydiaDonachie WilliamJaglarz Anita Dorota

(73)

Holder

Zoetis Servisiz Lls

OIL-BASED ADJUVANTS Russian patent published in 2020 - IPC A61K39/39 A61K9/107 A61P1/00

Abstract RU 2730011 C2

FIELD: pharmaceuticals.

SUBSTANCE: group of inventions relates to a vaccine composition for treating and preventing enteritis and a method of treating or preventing enteritis caused by BCV or BRV in cattle. Vaccine composition contains an effective amount of at least one of BRV and BCV antigen and adjuvant composition containing mineral oil, emulsifier, CpG-containing immunostimulating oligonucleotide, an aluminum source and, optionally, a polycationic carrier taken in a certain ratio. A method of treating or preventing enteritis in cattle involves administering a vaccine composition.

EFFECT: group of inventions provides an effective stable vaccine composition for treating or preventing enteritis caused by BCV or BRV.

7 cl, 49 tbl, 15 ex

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RU 2 730 011 C2

Authors

Dominowski Paul Joseph

Wilmes Lauren

Foss Dennis L.

Mohr Kaori

Gallo Guillermo

Hardham John Morgan

Krebs Richard Lee

Lightle Sandra Ann Marie

Mahan Suman

Mediratta Sangita

Mwangi Duncan

Rai Sharath K.

Salmon Sarah A.

Vora Shaunak

Fontaine Michael Christopher

Smith David George Emslie

Fitzpatrick Julie Lydia

Donachie William

Jaglarz Anita Dorota

Dates

2020-08-14—Published

2014-09-19—Filed