OPHTHALMIC PREPARATION IN THE FORM OF EYE DROPS FOR PREVENTING AND TREATING INFECTIOUS CONJUNCTIVITIS CAUSED BY BACTERIA AND VIRUSES Russian patent published in 2019 - IPC A61K9/08 A61K31/155 A61K47/22 A61K47/38 A61P27/02 A61P31/04 A61P31/12 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to ophthalmology, and aims at preventing and / or treating infectious conjunctivitis. Ophthalmic preparation in the form of eye drops for preventing and / or treating infectious conjunctivitis caused by bacteria and / or viruses contains an active ingredient, pharmaceutically acceptable excipients and water for injections. Said bacteria are selected from a group consisting of Streptococcus pneumoniae, Heamophilus influenzae, Moraxella catarrhalis, and the viruses are selected from a group consisting of adenoviruses Ad 4, Ad 5, Ad 6, Ad 8, Ad 11, Ad 13, Ad 19, Ad 37. Active component is branched oligohexamethylene guanidine (OHMG) succinate of formula (I)

, where R is represented by formulas (II) or (III)

and n1, n2 and n3 are equal to 1–3, z is equal to 0.15–1.10, with molecular weight distribution Mw/Mn from 5.4 to 9.3, with weight average molecular weight Mw ranging from about 3800 to 6300 Da and number average molecular weight Mn ranging from about 600 to 1100 Da. Pharmaceutically acceptable excipients are a) a viscosity modifier selected from polyvinyl alcohol, hydroxypropyl methyl cellulose and polyvinylpyrrolidone, b) an isotonicity regulator represented by sodium chloride, c) a pH regulator represented by a phosphate buffer consisting of potassium dihydrogen phosphate and potassium hydrophosphate. Components are used in claimed amounts.

EFFECT: use of the invention provides effective treatment and / or prevention of infectious conjunctivitis expressed in bacteriostatic / virostatic or bactericidal / virucidal actions against bacterial pathogens – Streptococcus pneumoniae, Heamophilus influenzae, Moraxella catarrhalis and adenoviral pathogens causing the corresponding conjunctivitis types, with lower toxicity and allergenicity.

1 cl, 4 ex