KOC1-DERVIED PEPTIDE AND VACCINE INCLUDING SAME Russian patent published in 2019 - IPC C07K7/06 A61K38/08 A61K35/12 A61K35/14 A61K39/00 A61K48/00 C12N15/09 C12N5/10 

Abstract RU 2699542 C2

FIELD: medicine.

SUBSTANCE: present invention also relates to polynucleotides coding peptides, antigen-presenting cells presenting peptides, and cytotoxic T-cells aimed at peptides, as well as to methods of inducing antigen-presenting cells or CTL. Present invention also relates to compositions and pharmaceutical compositions containing them as an active ingredient. Additionally, the present invention refers to methods of treating and/or preventing a malignant tumour and/or prevention of its postoperative relapse using peptides, polynucleotides, antigen-presenting cells, cytotoxic T-cells or pharmaceutical compositions according to the present invention. Methods of inducing an immune response against a malignant tumour are also provided.

EFFECT: invention relates to epitope peptides derived from KOC1, with the ability to induce cytotoxic T-cells.

19 cl, 16 dwg, 4 tbl, 5 ex

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RU 2 699 542 C2

Authors

Tsunoda Takuya

Osawa Ryuji

Yamashita Sachiko

Watanabe Tomohisa

Hikichi Tetsuro

Dates

2019-09-06Published

2015-07-31Filed