FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention refers to pharmaceutical industry, namely to a percutaneous absorption composition. Percutaneous absorption composition comprising testosterone, one or more organic solvents selected from a group consisting of propylene glycol, 1,3-butylene glycol, dipropylene glycol and polyethylene glycol, a gelling agent selected from a group of cellulose derivatives and acrylic acid-based polymers, water, wherein the composition does not contain a monohydric alcohol having from 2 to 4 carbon atoms, where components are taken in effective amounts.
EFFECT: proposed composition containing testosterone is effectively distributed due to high affinity to skin and adhesion on skin, stays stable on skin.
6 cl, 8 tbl, 49 ex
| Title | Year | Author | Number |
|---|---|---|---|
| TRANSDERMAL PHARMACEUTICAL COMPOSITIONS CONTAINING ACTIVE AGENTS | 2010 |
|
RU2639087C2 |
| FILM-FORMING PHARMACEUTICAL COMPOSITION FOR TRANSDERMAL ADMINISTRATION | 1996 |
|
RU2161957C2 |
| TOPICAL COMPOSITION | 2008 |
|
RU2497516C2 |
| RUPATADINE-CONTAINING PATCH | 2018 |
|
RU2776063C2 |
| TESTOSTERONE COMPOSITIONS | 2012 |
|
RU2613891C2 |
| MEDICAL COMPOSITION FOR PERCUTANEOUS ABSORBTION, PRODUCT KEEPING MEDICAL COMPOSITION, AND PREPARATION FOR PERCUTANEOUS ABSORBTION CONTAINING IT | 2008 |
|
RU2428186C2 |
| PHARMACEUTICAL COMPOSITION FOR LOCAL ADMINISTRATION | 2015 |
|
RU2703557C1 |
| PHARMACEUTICAL COMPOSITION | 1999 |
|
RU2203058C2 |
| PHARMACEUTICAL COMPOSITIONS OF THERAPEUTIC, ANTI-INFLAMMATORY AND ANALGETIC AGENT FOR TOPICAL APPLICATION AND METHOD OF THEIR PREPARING | 1996 |
|
RU2157689C2 |
| COMPOSITION FOR TRANSCUTANEOUS DELIVERY OF CATIONIC ACTIVE SUBSTANCES | 2009 |
|
RU2517241C2 |
