FIELD: biotechnology; medicine.
SUBSTANCE: present invention relates to biotechnology, specifically to production of antimicrobial peptides, and can be used in medicine for antimicrobial therapy. Polypeptide containing the sequence LKKLYKRLVKILKRWWRYLKRPVR or its modified version is highly effective against drug-resistant gram-positive and gram-negative bacteria, as well as against fungi. Besides, the polypeptide is able to prevent formation of a bacterial biofilm on plastic as well as biotic surfaces.
EFFECT: invention enables to obtain an agent with high antimicrobial activity.
13 cl, 3 dwg, 12 tbl, 1 ex
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