METHOD FOR DIFFERENTIAL DIAGNOSIS OF MUSCULAR HYPOTENSION OF CENTRAL AND PRIMARY-MUSCULAR GENESIS IN INFANTS Russian patent published in 2019 - IPC A61B5/488 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to neurology, and can be used for differential diagnosis of muscular hypotension of central genesis and myopathy in infants. It involves stimulating ENMG, needle EMG and surface EMG m. deltoideus, m. abductor digiti minimi, m. rectus femoris, m. abductor hallucis. With myopathy of amplitude of surface EMG m. deltoideus <300 mcV and m. rectus femoris <350 mcV, and amplitude of surface EMG m. abductor digiti minimi and m. abductor hallucis normal, amplitude of myotactic reflex <50 mcV. In muscular hypotension of central genesis of amplitude of surface EMG m. abductor digiti minimi and m. abductor hallucis <500 mcV, and amplitude of surface EMG m. deltoideus and m. rectus femoris are within normal range, amplitude of myotactic reflex >100 mcV. That is followed by stimulating ENMG, which involves estimating the amplitude of the M-response with m. biceps brachii, m. abductor digiti minimi, m. rectus femoris, m. abductor halluces. In myopagia, the M-response amplitude is <5 mV. Muscular hypotension of central genesis shows amplitude of M-responses. It is followed by needle EMG m. biceps brachii, m. rectus femoris. Duration of motor unit potentials (PDE), amplitude of PDE and number of phases are determined. If observing myopathy, the dose of PDE decreases by 13 % and more as compared with the norm, PDE amplitude m. biceps brachii <250 mV, amplitude of PDE m. rectus femoris <300 mcV, number of phases >4. If observing central muscular hypotension, parameters of PDE are within normal limits.

EFFECT: method provides differential diagnosis of muscular hypotension of primary-muscular genesis from muscular hypotension of central genesis ensured by application of complex ENMG methods.

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