N-SULPHONYL HOMOSERINE LACTONE DERIVATIVES, METHODS FOR PRODUCTION AND USE THEREOF Russian patent published in 2019 - IPC C07D409/12 C07D407/12 C07D405/12 C07D307/33 A61K31/381 A61K31/4025 A61K31/341 A61K31/443 A61P31/00 

FIELD: chemistry.

SUBSTANCE: invention relates to a homoserine lactone derivative of formula I or a pharmaceutically acceptable salt thereof, in which R denotes a group selected from thienyl, furyl and pyrrolyl, wherein said group can be monosubstituted, disubstituted or tri-substituted with a substituent selected from a group comprising halogen, nitro and C_1-6 alkyl. Invention also relates to a method of producing said derivative of formula I, as well as to a pharmaceutical composition for regulating the feeling of quorum in bacteria based on a derivative of formula I.

EFFECT: technical result is obtaining a novel compound of formula I and a pharmaceutical composition based thereon, which can be used in medicine for preventing and/or treating a disease caused by a bacterial infection.

8 cl, 2 tbl, 32 ex