FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and represents an antibody which specifically binds to B7-H1, or an antigen-binding fragment thereof for use in treating a patient having a tumour which expresses B7-H1, wherein the patient is detected by detecting B7-H1 expression in one or more tumour cells, and where 25 % or more tumour cells contain membrane staining by B7-H1, where the use additionally involves using 0.1, 0.3, 1, 3, 10, or 15 mg/kg of antibody or its antigen-binding fragment.
EFFECT: invention allows extending the range of antibodies to B7-H1.
11 cl, 25 dwg, 19 tbl, 4 ex
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Authors
Dates
2019-09-25—Published
2014-09-11—Filed