METHOD OF TREATING ACUTE MYOCARDIAL INFARCTION Russian patent published in 2019 - IPC A61K31/277 A61K31/50 A61K33/14 A61P9/10 

Abstract RU 2702146 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to cardiology, X-ray endovascular methods of diagnosis and treatment. Performing selective catheterisation and coronary angiography of coronary arteries and arterial shunts following percutaneous coronary intervention or coronary artery bypass. If observing angiograms of coronary artery or coronary artery spasm directly in the coronary artery or coronary artery bypass, medications are introduced: 1 ml of solution containing 100 mcg of verapamil at rate of 0.1 ml per second. That is followed by administering 10 ml of 0.9 % sodium chloride solution for 1–2 seconds. That is followed by administering 5 ml of solution containing 2.5 mg of levosmendan at rate of 1 ml per second, then adding 10 ml of solution of 0.9 % sodium chloride for 1–2 seconds.

EFFECT: method enables causing smooth muscle relaxation of a coronary artery vascular wall and recovering blood flow by coronary arteries by using two preparations of verapamil and levosimendan, having pronounced pharmacological action on the smooth muscles of the vascular wall of arteries in acute myocardial infarction caused by pronounced spasm or "no-reflow" phenomenon following percutaneous coronary intervention or aortocoronary shunting.

1 cl, 22 dwg, 2 ex

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RU 2 702 146 C1

Authors

Stolyarov Dmitrij Pavlovich

Sakovich Valerij Anatolevich

Sakhnov Evgenij Vladimirovich

Melnikov Aleksandr Viktorovich

Fursov Aleksandr Anatolevich

Dates

2019-10-04Published

2018-12-18Filed