FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to oncodiagnosis, and can be used for detecting neoplastic cell degeneration caused by human papilloma virus (HPV) in females undergoing screening for cervical cancer. That is ensured by detecting cell samples taken from squamous cell-cylinder cell junction of epithelium of cervix uterus of patient being tested, protein complex E6 / p53 consisting of protein E6 and protein p53, and protein complex E7/rRB consisting of protein E7 and protein pRB. Detection of said two protein complexes shows that the patient's cancer carcinogenesis has become irreversible, and said detection is carried out with combined use of antibodies to E6 protein, E7 protein antibodies, antibodies to p53 protein and antibodies to protein pRB.
EFFECT: invention provides diagnosing cervical cancer.
14 cl, 8 dwg, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF COMBINED THERAPY OF CERVICAL DYSPLASIA ASSOCIATED WITH HUMAN PAPILLOMA VIRUSES | 2019 |
|
RU2701525C1 |
| STABLE VECTOR OF CONSTITUTIVELY HIGH EXPRESSION FOR OBTAINING HPV VACCINE, AND RECOMBINANT LACTIC ACID BACTERIA TRANSFORMED BY THIS VECTOR | 2010 |
|
RU2492240C2 |
| METHOD FOR EARLY AND PRECLINICAL DIAGNOSTICS OF CERVICAL CANCER | 2003 |
|
RU2251699C1 |
| MUCOSAL VACCINE FOR IMMUNE THERAPY OF DISEASES CAUSED BY HUMAN PAPILLOMA VIRUSES, AND RELATED THERAPY (VERSIONS) | 2008 |
|
RU2377305C1 |
| DIAGNOSTIC TECHNIQUE FOR HYPERPROLIFERATIVE CONDITIONS AND METHOD FOR ASSESSING RISK OF CERVICAL CANCER ACCOMPANYING CERVICAL INTRAEPITHELIAL NEOPLASIA AND PAPILLOMA VIRUS CARRIER STATE BY DETERMINIG MRNA OF FUNCTIONAL HUMAN GENE COMPLEX | 2012 |
|
RU2532344C2 |
| COMBINATION OF POXVIRUS ENCODING HUMAN PAPILLOMA VIRUS POLYPEPTIDES, AND IL-2 WITH ANTI-PD-L1 ANTIBODY | 2020 |
|
RU2824962C1 |
| IMMUNOGENIC COMPOSITION BASED ON RECOMBINANT PROTEINS E6-CBD AND E7-CBD FOR THE TREATMENT OF MALIGNANT NEOPLASMS ASSOCIATED WITH HUMAN PAPILLOMAVIRUS TYPE 16 | 2023 |
|
RU2805482C1 |
| METHOD OF EXAMINING STATE OF CERVIX | 2023 |
|
RU2833119C1 |
| 3,3'-DIINDOLYLMETHANE (METINDOL)-BASE VAGINAL SUPPOSITORY | 2006 |
|
RU2318510C1 |
| PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DYSPLASTIC PROCESSES OF CERVIX | 2008 |
|
RU2395281C2 |
