FIELD: medicine.
SUBSTANCE: invention refers to medicine, particularly to hematology, and aims at treating immune thrombocytopenia (ITP). Allelic polymorphism of glycoprotein genes GpIIb T2622G and GpIa A1648G responsible for formation of HPA-3 and -5 systems, respectively. If observing the genotype GpIIb heterozygote, genotype 2622TG is followed by corticosteroid therapy. If observing genotype GpIa homozygotes of genotype 1648AA, splenectomy or therapy with thrombopoietin receptor agonists is performed.
EFFECT: proposed method enables optimizing the management of the ITP based on studying the genetic characteristics of the individual patient and significantly reducing the cost of the therapy.
1 cl, 3 ex
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