FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, namely to a method for determining antagonistic activity of bacterial strains with respect to Pseudomonas aeruginosa, including culturing Pseudomonas aeruginosa and tested strains on nutrient media, characterized by that the antiviral activity of the tested strains is detected by evaluating the production of oxyphenazines P. aeruginosa in the presence of tested strains compared to pure culture P. aeruginosa based on spectrophotometric evaluation of their content in extracts, and when observing suppression of oxyphenazine production, antagonistic activity of test strain is detected.
EFFECT: use of the method enables assessing antagonist activity of growth inhibitory bacteria Pseudomonas aeruginosa and preventing accumulation of pathogenicity factors associated with formation of biofilms.
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