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2 704 326

(13)

(51)

IPC

A61K31/704(2006-01-01)

C07H15/252(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2019121378, 2019-07-09

(24)

Start date

2019-07-09

(22)

Actual filing date

2019-07-09

(45)

Published

2019-10-28

(72)

Inventor

Artyushin Oleg IvanovichMoiseeva Aleksandra AndreevnaBrel Valerij KuzmichAnikina Lada Vladimirovna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Elementoorganicheskikh Soedinenij Im. A.N. Nesmeyanova Rossijskoj Akademii Nauk Ran)

N-METHOXYBENZYL DERIVATIVES OF DAUNORUBICIN HAVING ANTIPROLIFERATIVE PROPERTIES Russian patent published in 2019 - IPC A61K31/704 C07H15/252 A61P35/00

Abstract RU 2704326 C1

FIELD: chemistry.

SUBSTANCE: invention relates to N-methoxybenzyl derivatives of daunorubicin of general formula I, where R=H, OCH₃.

EFFECT: obtaining novel compounds having good antiproliferative properties with relatively low acute toxicity, which can be used in medicine for treating oncological diseases, in particular non-small-cell lung cancer, rhabdomyosarcoma, intestinal carcinoma, adenocarcinoma of the mammary gland.

1 cl, 1 tbl, 2 ex

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RU 2 704 326 C1

Authors

Artyushin Oleg Ivanovich

Moiseeva Aleksandra Andreevna

Brel Valerij Kuzmich

Anikina Lada Vladimirovna

Dates

2019-10-28—Published

2019-07-09—Filed