METHOD OF MAKING DISK SECTORS FOR CAPTURING, RETAINING AND ANALYZING MAGNETIC MICROPARTICLES AND LABELED BIOLOGICAL OBJECTS ON THE SURFACE OF SPIN GATES BY MEANS OF FEMTOSECOND LASER RADIATION Russian patent published in 2019 - IPC G01R33/12 B82Y25/00 G16H10/40 

Abstract RU 2704972 C1

FIELD: medicine.

SUBSTANCE: invention relates to development of new generation biomedical sensors, namely to creation of sectors on the surface of spintronics devices. In biomedicine, separation of healthy and diseased cells is based on different probability of capturing magnetic nanoparticles or microparticles by cells depending on their state. Result of separation of healthy and diseased cells of proteins in a magnetic column requires rapid analysis of degree of their separation. Disclosed method of making disk sectors for capturing, holding and analyzing magnetic microparticles and marked biological objects on the surface of spin gates by means of femtosecond laser irradiation involves laser irradiation of the surface of heterostructure SiO2/Ta/Pt/GdFeCo/IrMn/PtE with an ultrashort pulse duration of 30–50 fs to formation of disk sectors with diameter of 3–10 mcm and depth of 10–30 nm on surface of heterostructure SiO2/Ta/Pt/GdFeCo/IrMn/PtE, wherein the fluence is selected in range of 10–20 mJ/cm2, with subsequent determination of gradient of scattering magnetic field created by edges of disc sectors, state of material magnetization inside disc sectors, local chemical composition of material inside disk sectors and surface topology in disc sectors and around it, local mechanical properties (Young's modulus and microhardness) inside disk sectors.

EFFECT: development of a less expensive and labor-intensive method of making disc sectors, or craters, for gripping, holding and analyzing magnetic microparticles and marked biological objects on the surface of spin gates.

5 cl, 10 dwg

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RU 2 704 972 C1

Authors

Aldoshin Sergej Mikhajlovich

Palij Andrej Vladimirovich

Morgunov Roman Borisovich

Koplak Oksana Vyacheslavovna

Bezverkhnij Aleksandr Ivanovich

Dates

2019-11-01Published

2019-07-16Filed