FIELD: biotechnology.
SUBSTANCE: group of inventions relates to antibodies that bind to human interleukin-6 (IL6), as well as to a composition and combination for the treatment of IL6 associated diseases, and a pharmaceutical composition for use in the treatment of IL6 associated diseases containing thereof. Invention also relates to a method for treating IL6 associated diseases and administering a therapeutically effective amount of an antibody for treating IL6 associated diseases, or for the preparation of a medicament for the treatment of the IL6 associated diseases or conditions. Also provided is a nucleic acid encoding an antibody, an antibody cloning vector, an antibody expression vector, a host cell for preparation, and a method for producing an antibody.
EFFECT: group of inventions provides effective treatment of IL6 associated diseases.
41 cl, 9 dwg, 3 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ANTIBODIES RAISED TO HUMAN MCP-1 | 2001 |
|
RU2314316C2 |
| ANTIBODY TO CLDN18.2 AND ITS USE | 2018 |
|
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|
RU2577977C2 |
| BLOCKING ANTI-Dkk-1 ANTIBODIES AND APPLICATIONS THEREOF | 2010 |
|
RU2548817C2 |
| MOLECULES WHICH BIND TO 4-1BB | 2011 |
|
RU2710717C2 |
| COMPOSITIONS AND METHODS FOR SUPPRESSION OF CANCER STEM CELLS | 2016 |
|
RU2752610C1 |
| J591 MINIBODIES AND CYS-DIABODIES FOR TARGETED DELIVERY OF HUMAN PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) AND METHODS FOR THEIR USE | 2010 |
|
RU2673908C2 |
| ANTIBODIES AGAINST EOTAXIN 2, WHICH RECOGNIZE ADDITIONAL CCR3-BINDING CHEMOKINES | 2015 |
|
RU2705255C2 |
| ANTIBODIES SPECIFICALLY BOUND TO EPIDERMAL GROWTH FACTOR RECEPTORS | 2009 |
|
RU2518239C2 |
