METHOD OF TREATING OPERABLE PANCREATIC HEAD ADENOCARCINOMA Russian patent published in 2019 - IPC A61K31/00 A61K31/337 A61K31/555 A61K31/7068 A61K35/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to a method of treating operable pancreatic head adenocarcinoma. Method of treating operable pancreatic adenocarcinoma, including intra-arterial administration of chemotherapeutic agents Abraxane and gemcitabine, wherein the chemopreparations are additionally oxaliplatin, which is introduced through a catheter inserted into a gastroduodenal artery, infusion, then bolus Abraxane, performing selective tumor embolization, after which the catheter is reinserted into the celiac and the gemcitabine is infused, not earlier than one day after the chemotherapy, sessions of the conformal radiation therapy are performed; surgical removal of the tumor is performed not earlier than the day after the end of the radiation therapy, after which no earlier than 2 weeks later infusion of gemcitabine is introduced into a cogwheel, then no later than 4 weeks, systemic adjuvant chemotherapy is performed by oral administration of capecitabine and simultaneous intravenous administration of gemcitabine, implementing such administration of these preparations for not more than 4 months or until occurrence of undesired phenomena of II-III degree or progression of tumor process according to RECIST criteria, taken in certain proportions and under certain conditions.

EFFECT: method described above provides improved clinical results in patients with operable pancreatic head adenocarcinoma in the form of an increase in the recurrence-free period and overall survival of the patients.

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