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2 707 548

(13)

(51)

IPC

C12N1/20(2006-01-01)

C12Q1/04(2006-01-01)

(21) (22)

Application

2019101942, 2019-01-24

(24)

Start date

2019-01-24

(22)

Actual filing date

2019-01-24

(45)

Published

2019-11-27

(72)

Inventor

Egorova Svetlana AleksandrovnaKaftyreva Lidiya Alekseevna

(73)

Holder

Federalnoe Byudzhetnoe Uchrezhdenie Nauki Nauchno-Issledovatelskij Institut Epidemiologii I Mikrobiologii Im. Pastera Federalnoj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchiya Cheloveka" Nii Epidemiologii I Mikrobiologii Imeni Pastera)

STRAIN OF BACTERIA SALMONELLA ENTERICA SUBSPECIES ENTERICA SEROVAR TYPHI B-8453 WITH LOW LEVEL RESISTANCE TO FLUOROQUINOLONES, USED AS A CONTROL STRAIN FOR PHENOTYPIC AND MOLECULAR STUDIES IN DIAGNOSING TYPHOID FEVER Russian patent published in 2019 - IPC C12N1/20 C12Q1/04

Abstract RU 2707548 C1

FIELD: microbiology.

SUBSTANCE: invention relates to bacteriology. Disclosed is a strain of Salmonella enterica sbsp. enterica serovar Typhi B-8453, characterized by low level resistance to fluoroquinolones caused by a mutation in chromosomal gene gyrA of Ser83Tyr type. Presented strain is deposited in the State collection of pathogenic microorganisms and cell cultures "GKPM-Obolensk" under registration number B-8453. Strain can be used as a control strain for phenotypic (detection of resistance of low level to fluoroquinolones) and molecular (detection of a mutation in gene gyrA of Ser83Tyr type) of researches at diagnostics of typhoid fever.

EFFECT: disclosed is a strain of bacteria Calmonella enterica subspecies enterica serovar Typhi B-8453 with low level resistance to fluoroquinolones, used as a control strain for phenotypic and molecular studies in diagnosing typhoid fever.

1 cl, 4 ex

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RU 2 707 548 C1

Authors

Egorova Svetlana Aleksandrovna

Kaftyreva Lidiya Alekseevna

Dates

2019-11-27—Published

2019-01-24—Filed